About 1 result found for searched term "Apostatin-1" (0.199 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M21568 | Apostatin-1 | RIPK |
| Apt-1 | ||
| Apostatin-1 (Apt-1) is a new type of TRADD inhibitor. Apostatin 1 can bind to TRADD-N (KD=2.17 μM), and destroy the binding of Apostatin 1 to TRADD-C and TRAF2. Apostatin-1 regulates ubiquitination of RIPK1 and beclin 1. By activating autophagy in cells accumulated by mutated tau, α-synuclein or huntingtin, Apostatin 1 blocked apoptosis and restored homeostasis. | ||
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