About 3 results found for searched term "Apilimod" (0.127 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9332 | Apilimod | Others |
| STA-5326; LAM-002A free base; AIT-101 | ||
| Apilimod is a potent IL-12/IL-23 inhibitor, and it is also a cell permeable small molecule which specifically inhibits PIKfyve with an IC50 of 14 nM in an in vitro kinase assay. | ||
| M9418 | Apilimod mesylate | IL Receptor/Related |
| STA 5326 mesylate | ||
| Apilimod mesylate is a potent IL-12/IL-23 inhibitor, which inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively Apilimod is also a potent and highly selective PIKfyve inhibitor. | ||
| M40745 | PIK5-12d | PROTAC |
| PIK5-12d is a highly active and selective PIKfyve degrader constructed based on the PIKfyve inhibitor Apilimod and VHL ligand. It can effectively inhibit the autophagy pathway in a variety of prostate cancer cells by degrading PIKfyve, and significantly induce pronounced vacuolization of tumor cytoplasm. | ||
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