Amitriptyline - Search Results

About 4 results found for searched term "Amitriptyline" (0.134 seconds)

Cat.No.	Name	Target
M2388	Amitriptyline hydrochloride	5-HT Receptor
	Amitriptyline inhibits serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with IC50 of 3.45 nM, 13.3 nM, 7.31 nM, 235 nM and 287 nM, respectively.
M5824	Nortriptyline hydrochloride	Autophagy
	Desmethylamitriptyline hydrochloride
	Nortriptyline hydrochloride is a tricyclic antidepressant used to relieve the symptoms of depression.
M20793	Amitriptyline	Serotonin Transporter
	MK-230; N-750; Ro41575
	Amitriptyline (MK-230, N-750, Ro41575) is an inhibitor of the serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki values of 3.45 nM and 13.3 nM, respectively, and also inhibits the histamine receptor H1, the histamine receptor H4, 5-HT2, and the Sigma 1 receptor with Ki values of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. It can also inhibit histamine receptor H1, histamine receptor H4, 5-HT2 and Sigma 1 receptor with Ki values of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively, and can be used in studies of depression and neuropathic pain.
M41734	Amitriptylinoxide	5-HT Receptor
	Amitriptylinoxide (Equilibrin) is an analogue and metabolite of amitriptyline with similar antidepressant efficacy.