About 3 results found for searched term "Agomelatine" (0.132 seconds)
Cat.No. | Name | Target |
---|---|---|
M2230 | Agomelatine | Melatonin Receptor |
Valdoxan; Melitor; S-20098 | ||
Agomelatine is a metabolically stable analog of melatonin that displays agonist activity for MT1 and MT2 binding with nanomolar affinity. Agomelatine is also a selective 5-HT2C receptor antagonist with pKis of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively. | ||
M14012 | Agomelatine hydrochloride | Others |
S-20098 hydrochloride | ||
Agomelatine hydrochloride (S-20098 hydrochloride) is a specific agonist of MT1 and MT2 receptors with Kis of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively. | ||
M14013 | Agomelatine (L(+)-Tartaric acid) | Melatonin Receptor |
S-20098 L(+)-Tartaric acid | ||
Agomelatine L(+)-Tartaric acid (S-20098 L(+)-Tartaric acid) is a specific agonist of MT1 and MT2 receptors with Kis of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively. |
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