About 15 results found for searched term "Adenylate Cyclase" (0.144 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2191 | Forskolin | Adenylate Cyclase |
| Coleonol; Colforsin; HL 362 | ||
| Forskolin is a diterpenoid natural product extracted from the hairy throat sphagnum flower (Coleus forskohlii), and is also a eukaryotic adenylate cyclase (AC) activator, which can increase cAMP levels. In addition, Forskolin can be used as a substitute for Oct4 in the induction and maintenance of pluripotent stem cells in mice and promotes osteoblast differentiation in vitro with potential anti-osteoporotic activity. | ||
| M7031 | NKH 477 | Adenylate Cyclase |
| NKH477 | ||
| NKH477 (Colforsin dapropate hydrochloride) directly activates the catalytic unit of adenylate cyclase and increases intracellular cAMP. NKH477 can inhibit acute rejection of orthotopic lung allograft in rats by inhibiting proliferation in vivo. | ||
| M7693 | Chloro-APB hydrobromide | Dopamine Receptor |
| (±)-SKF 82958; Chloro-AP | ||
| Chloro-APB hydrobromide is a selective dopamine D1 receptor agonist and induces dopamine D1 receptor-dependent adenylate cyclase activity in rat striatal membranes (EC50=491 nM). | ||
| M7874 | KH7 | Adenylate Cyclase |
| KH7 is a specific inhibitor of soluble adenylate cyclase (sAC) with IC50 values of 3-10 μM against recombinant sACt proteins (human and others) in cells. KH7 is also an inhibitor of cAMP. | ||
| M10161 | PACAP (1-38) | Peptides |
| PACAP (1-38) is a highly potent PACAP receptor agonist (Kd = 100 pM), it stimulates adenylate cyclase and phagocytosis. | ||
| M11311 | BMS-986122 | Opioid Receptor |
| BMS986122, BMS 986122 | ||
| Bms-986122 is a selective and effective positive allosteric regulator of μ -opioid receptor (µ-OR). Bms-986122 showed enhancement of β -inhibitory protein recruitment, adenylate cyclase inhibition and G-protein activation mediated by normal agonists. Bms-986122 enhances damGO-mediated [35S]GTPγS binding in mouse meninges. | ||
| M11321 | Angiopeptin TFA | Somatostatin Receptor |
| Angiopeptin TFA, a cyclic octapeptide analog of somatostatin, is an SST2 / SST5 receptor partial agonist with IC50 values of 0.26 nM and 6.92 nM, respectively. Angiopeptin TFA inhibits growth hormone release and insulin-like growth factor-1 (IGF-1) production. Angiopeptin TFA inhibits adenylate cyclase or stimulates extracellular acidification. Angiopeptin TFA has the potential to be used in the study of coronary atherosclerosis. | ||
| M25541 | SKF-82958 hydrobromide | Dopamine Receptor |
| (±)-SKF-82958 hydrobromide; Chloro-APB hydrobromide | ||
| SKF-82958 ((±)-SKF 82958) hydrobromide is a dopamine D1 receptor full agonist (K0.5=4 nM), displays selective for D1 over D2 receptors (K0.5=73 nM). SKF-82958 hydrobromide induces dopamine D1 receptor-dependent adenylate cyclase activity in rat striatal membranes (EC50=491 nM). | ||
| M13886 | Fipexide | Adenylate Cyclase |
| FPX | ||
| Fipexide, a parachloro-phenossiacetic acid derivative. Fipexide (FPX) is a novel chemical inducer that promotes callus formation and shoot regeneration in plants. Fipexide reduces striatal adenylate cyclase activity. Fipexide has positive effect on cognitive performance by dopaminergic neurotransmission. Fipexide is used for senile dementia research. | ||
| M28432 | PA-9 | Others |
| PA-9 is a pituitary adenylate cyclase-activating polypeptide (PACAP) type I (PAC1) receptor antagonist. PA-9 dose dependently inhibits PACAP-induced cAMP elevation with an IC50 of 5.6 nM. PA-9 can be used for the research of neuropathic and/or inflammatory pain. | ||
| M29123 | Adenosine 5'-diphosphate sodium salt | Metabolite/Endogenous Metabolite |
| Adenosine 5'-diphosphate (ADP) sodium salt is a nucleoside diphosphate, which is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate sodium salt induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors. | ||
| M30203 | Lysipressin | Adenylate Cyclase |
| Lysine vasopressin; [Lys8]-Vasopressin | ||
| Lysipressin (Lysine vasopressin) is antidiuretic hormone that have been found in pigs and some marsupial families. Lysipressin induces contraction of the rabbit urinary bladder smooth muscle, activate adenylate-cyclase. | ||
| M30674 | Lysipressin acetate | Adenylate Cyclase |
| Lysine vasopressin acetate; [Lys8]-Vasopressin acetate | ||
| Lysipressin (Lysine vasopressin) acetate is antidiuretic hormone that have been found in pigs and some marsupial families. Lysipressin acetate induces contraction of the rabbit urinary bladder smooth muscle, activate adenylate-cyclase. | ||
| M53227 | [Tyr22] Calcitonin Gene Related Peptide, (22-37), rat | CGRP Receptor |
| [Tyr22] Calcitonin Gene Related Peptide, (22-37), rat is a fragments 22-37 of rat calcitonin gene related peptide (CGRP), targeting CGRP receptor and adenylate cyclase. | ||
| M54475 | Small Cardioactive Peptide B (SCPB) | Adenylate Cyclase |
| Small Cardioactive Peptide B (SCPB), a neurally active peptide, stimulates adenylate cyclase activity in particulate fractions of both heart and gill tissues with EC50s of 0.1 and 1.0 μM, respectively. | ||
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