About 1 result found for searched term "AZD3229" (0.147 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M20646 | AZD3229 | c-Kit |
| AZD3229 is a potent, pan-KIT mutant inhibitor with potent single digit nM growth inhibition against a diverse panel of mutant KIT driven Ba/F3 cell lines (GI50=1-50 nM), with good margin to KDR-driven effects. It also inhibits PDGFR mutants (Tel-PDGFRα, Tel-PDGFRβ, V561D/D842V). | ||
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