About 8 results found for searched term "AZ82" (0.058 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2295 | AZD6482 | PI3K |
| KIN 193 | ||
| AZD6482 is an inhibitor of PI3Kβ with IC50 of 21 nM. | ||
| M10702 | AZD5582 | IAP |
| AZD5582 is an IAP antagonist that can be effectively combined with bir3 domains of cIAP1, cIAP2, and XIAP, IC50 The values are 15, 21, 15 nM, respectively. AZD5582 Induces apoptosis. | ||
| M13687 | AZ82 | Kinesin |
| AZ82 is a selective kinesin-like protein KIFC1 (HSET/KIFC1) inhibitor, with a Ki of 43 nM and an IC50 of 300 nM for KIFC1. | ||
| M14857 | (Rac)-AZD 6482 | PI3K |
| (Rac)-KIN-193 | ||
| (Rac)-AZD 6482 ((Rac)-KIN-193) is the racemate of AZD 6482. AZD 6482 is a potent and selective p110β inhibitor with an IC50 of 0.69 nM. | ||
| M21069 | AZ13824374 | Epigenetic Reader Domain |
| AZ13824374 is an in vitro ATAD2 inhibitor with anti-proliferative activity against breast cancer. pIC50 of AZ13824374 against ATAD2 in the ATAD2 FRET and ATAD2 NanoBRET assays were 8.2 and 6.2, respectively. | ||
| M28932 | AZ9482 | PARP |
| AZ9482 is a triple PARP1/2/6 inhibitor, with IC50 values of 1 nM, 1 nM and 640 nM for PARP1, PARP2 and PARP6, respectively. | ||
| M45105 | Naproxcinod | COX |
| AZD 3582; HCT 3012; Nitronaproxen | ||
| Naproxcinod is a first-of-its-kind (first-in-class) cyclooxygenase-inhibiting nitric oxide donors (CINODs) with analgesic and anti-inflammatory activity for studies related to osteoarthritis and inflammation. | ||
| M45125 | AZD-8233 | PCSK9 |
| AZD-8233 is an orally active, antisense oligonucleotide (ASO) targeting PCSK9 that targets and inhibits the translation and protein synthesis of PCSK9 mRNA in hepatocytes and reduces circulating LDL-C levels. It can be used in studies related to hypercholesterolemia. | ||
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