About 1 result found for searched term "AZ194 " (0.127 seconds)
Cat.No. | Name | Target |
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M29408 | AZ194 | Sodium Channel |
AZ194 is a first-in-class, orally active inhibitor of CRMP2-Ubc9 interaction and inhibitor of NaV1.7 (IC50=1.2 μM). AZ194 blocks SUMOylation of CRMP2 to selectively reduce the amount of surface-expressed NaV1.7. Antinociceptive effects. |
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