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 About 1 result found for searched term "AZ194 " (0.127 seconds)

Cat.No.  Name Target
M29408 AZ194  Sodium Channel
AZ194 is a first-in-class, orally active inhibitor of CRMP2-Ubc9 interaction and inhibitor of NaV1.7 (IC50=1.2 μM). AZ194 blocks SUMOylation of CRMP2 to selectively reduce the amount of surface-expressed NaV1.7. Antinociceptive effects.



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