About 3 results found for searched term "AV-412" (0.128 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3217 | AV-412 | EGFR/HER2 |
| MP-412 | ||
| AV-412 is a second-generation, orally bioavailable dual EGFR/HER2 tyrosine kinase inhibitor. | ||
| M14131 | AV-412 free base | EGFR/HER2 |
| MP-412 free base | ||
| AV-412 free base (MP-412 free base) is an EGFR inhibitor with IC50s of 0.75, 0.5, 0.79, 2.3, 19 nM for EGFR, EGFRL858R, EGFRT790M, EGFRL858R/T790M and ErbB2, respectively. | ||
| M4801 | LCL161 | IAP |
| LCL-161 | ||
| LCL161 is an orally bioavailable SMAC mimetic, potently binds to and inhibits multiple IAPs (i.e. XIAP, c-IAP). LCL161 enhanced the proapoptotic effects of nilotinib and PKC412, against leukemic disease in vitro and potentiated the activity of both kinase inhibitors against leukemic disease in vivo. | ||
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
