About 2 results found for searched term "ATP-Red 1" (0.126 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M58575 | ATP-Red 1 | Fluorescent Dye |
| ATP-Red 1 is a multisite-binding switchable fluorescent probe, and it can selectively and rapidly responds to intracellular concentrations of ATP in living cells. Live-cell imaging indicated that ATP-Red 1 mainly localized to mitochondria with good biocompatibility and membrane penetration. ATP-Red 1 is a useful tool for investigating ATP-relevant biological processes. | ||
| M27669 | E1231 | Sirtuin |
| 1-{4-[2-(5-Methylfuran-2-yl)quinoline-4-carbonyl]piperazin-1-yl}ethan-1-one | ||
| E1231 is an orally active activator of Sirtuin 1 (SIRT1) (EC50=0.83 μM), to modulate cholesterol and lipid metabolism. E1231 interactes with SIRT1 (KD=9.61 μM) and deacetylated liver X receptor-alpha (LXRα), and increases ATP-binding cassette transporter A1 (ABCA1) expression. E1231 also reduces atherosclerotic plaque development in ApoE-/- mice model. E1231 can be used for research in cholesterol and lipid disorder-related diseases. | ||
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