About 1 result found for searched term "AS-99 TFA" (0.176 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M21507 | AS-99 TFA | Histone Methyltransferase |
| AS-99 TFA is the first-in-class, effective and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 µM, Kd= 0.89 µM) with anti-leukemia activity. In vivo, AS-99 TFA blocked cell proliferation, induced apoptosis and apoptosis, down-regulated MLL fusion target genes, and alleviated leukaemia. | ||
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