About 32 results found for searched term "ANTS" (0.062 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M18534 | (±)-Prantschimgin | Others |
| (±)-Prantschimgin | ||
| M25490 | ANTS | Fluorescent Dye |
| ANTS is a fluorescent dye. ANTS and DPX are encapsulated in liposomes can be an effective approach for measuring membrane leakage. | ||
| M2067 | AGI-5198 | Isocitrate Dehydrogenase (IDH) |
| IDH-C35 | ||
| AGI-5198 (IDH-C35) is the first highly potent and selective inhibitor of IDH1 R132H and R132C mutants in vitro with IC50 values of 0.07 μM and 0.16 μM, respectively. | ||
| M2389 | Amoxapine | Others |
| CL-67772 | ||
| Amoxapine is a tricyclic dibenzoxazepine (an N-aryl piperazine) which acts similarly to several other tricyclic antidepressants, amoxapine inhibits GLYT2a transport activity with IC50 of 92 μM. | ||
| M2443 | Benzoic Acid | Metabolite/Endogenous Metabolite |
| Benzoic acid is a colorless crystalline solid and a simple aromatic carboxylic acid, used as a food preservative. Benzoic acid is an aromatic alcohol existing naturally in many plants and is a common additive to food, drinks, cosmetics and other products. It acts as preservatives through inhibiting both bacteria and fungi. | ||
| M2666 | Emetine | Anti-infection |
| Emetine is a potent protein synthesis inhibitor in mammalian cells, plants and yeasts. | ||
| M2710 | FMK | S6 Kinase |
| RSK2 kinase inhibitor | ||
| FMK is a potent and selective inhibitor of p90 ribosomal protein S6 kinaseRSK2 (wt) with IC50 of 15 nM, >600- and 200-fold selectivity for RSK2 than the C436V and T493M mutants. | ||
| M3218 | PKI-402 | PI3K |
| PKI-402 is a potent dual pan-PI3K/mTOR inhibitor targeting PI3Kα/β/γ/δ and mTOR with IC50 of 2 nM/7 nM/16 nM/14 nM and 3 nM, respectively; also potent to PI3Kα mutants E545K and H1047R. | ||
| M3351 | Methoxsalen | Others |
| 8-Methoxypsoralen; Xanthotoxin; 8-MOP | ||
| Methoxsalen (Oxsoralen) a naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia, is an agent used to treat psoriasis, eczema, vitiligo and some cutaneous Lymphomas in conjunction with exposing the skin to sunlight. | ||
| M3422 | Capsaicin | TRP Channel |
| Qutenza; Vanilloid; (E)-Capsaicin | ||
| Capsaicin is an active component of chili peppers, which are plants belonging to the genus Capsicum. | ||
| M3484 | Dolutegravir | Integrase |
| GSK1349572 | ||
| Dolutegravir (GSK1349572) is a two-metal-binding HIV integrase inhibitor with IC50 of 2.7 nM, modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. | ||
| M3515 | MK-2461 | c-Met |
| MK-2461 is a potent, multi-targeted inhibitor for c-Met(WT/mutants) with IC50 of 0.4-2.5 nM, less potent to Ron, Flt1; 8- to 30-fold greater selectivity of c-Met targets versus FGFR1, FGFR2, FGFR3, PDGFRβ, KDR, Flt3, Flt4, TrkA, and TrkB. | ||
| M3894 | Rutin | Amyloid |
| Rutoside; Quercetin 3-O-rutinoside | ||
| Rutin is a flavonol glycoside found in many plants including buckwheat, tobacco, forsythia, hydrangea, viola, etc., which possesses healthy effects for human. | ||
| M3908 | Protocatechualdehyde | ROS |
| Protocatechuic aldehyde | ||
| Protocatechualdehyde (PCA) is a natural polyphenol compound isolated from the root of the herb S. miltiorrhiza and barley tea plants. | ||
| M3914 | Gallic acid | Thrombopoietin/Thrombin |
| 3,4,5-Trihydroxybenzoic acid | ||
| Gallic acid is an antiinflammatory substance found in plants and has been shown to Induce apoptosis in human lung cancer cells. | ||
| M3921 | Dioscin | Autophagy |
| CCRIS 4123, Collettiside III | ||
| Dioscin (CCRIS 4123, Collettiside III) is a natural steroid saponin derived from several plants, showing potent anti-cancer effect against a variety of tumor cell lines. | ||
| M3922 | Gracillin | STAT |
| NSC-698787 | ||
| Gracillin is a glycoside, more particularly to a Spirostanol saponin, which can be found among others in many plants of the genus Dioscorea, Paris and Costacea, for example in tamus communis. | ||
| M3966 | Oxysophocarpine | Others |
| OSC | ||
| Oxysophocarpine (OSC), a quinolizidine alkaloid extracted from leguminous plants of the genus Robinia, is traditionally used for various diseases including neuronal disorders. | ||
| M3971 | Isosteviol | ROS |
| Ketoisostevic Acid,NSC 231875 | ||
| Isosteviol is a tetracyclic diterpenoid obtained by acid hydrolysis of steviol glycoside extracts isolated from abundant Stevia rebaudiana plants. | ||
| M3979 | Caffeic acid | HDAC |
| Caffeic acid is an endogenous phenolic phytochemical compound that exists in plants and many foods. | ||
| M4179 | Neochlorogenic-acid | NF-κB |
| trans-5-O-Caffeoylquinic acid | ||
| Neochlorogenic acid is a natural polyphenolic compound found in dried fruits and other plants. Neochlorogenic acid can inhibit the production of TNF-α and IL-1β. Neochlorogenic acid inhibited the expression of iNOS and COX-2 proteins. Neochlorogenic acid also inhibited the activation of phosphorylated NF-κB P65 and P38 MAPK. | ||
| M4250 | Schisandrin-C | Apoptosis |
| Schizandrin C; Wuweizisu-C | ||
| Schisandrin-C is a natural product extracted from seeds, stems and other plants of Schisandra chinensis (Turcz.) Baill, which has antiviral, anti-cancer, anti-inflammatory and other activities. | ||
| M4302 | Solasodine | p53 |
| Purapuridine; Solancarpidine; Solasodin | ||
| Solasodine (Purapuridine) is a steroid alkaloid found in solanaceae plants. Solasodine has neuroprotective, antifungal, antihypertensive, anticancer, antiatherosclerotic, antiandrogen and anti-inflammatory activities. | ||
| M4345 | Barlerin | NF-κB |
| 8-O-Acetyl shanzhiside methyl ester | ||
| Barlerin (8-O-acetyl Shanzhiside methyl ester) is a cyclosporin glucoside isolated from folk medicinal plants in Xizang, China. Barlerin (8-O-acetyl Shanzhiside methyl ester) inhibited NF-κB activity. | ||
| M4548 | Vitexin | Autophagy |
| Vitexin is a C-glycosylated flavonoid found in a variety of medicinal plants such as Ficus deltoid and Spirulina (Spirodela polyrhiza). Vitexin has a wide range of pharmacological effects, including antioxidant, anticancer, anti-inflammatory, anti-hyperalgesia and neuroprotective effects. | ||
| M4560 | Paeonolide | Others |
| Paeonolide is a plant glycoside containing a non-reducing terminal α -1-arabopyranoside, which is present in the roots of a wide range of plants of the Genus Paeonia. | ||
| M4691 | Lycorine hydrochloride | HCV Protease |
| Lycorine-chloride | ||
| Lycorine hydrochloride is a natural alkaloid extracted from Amaryllidaceae (Amaryllidaceae) plants. It is a strong HCV inhibitor and melanoma angiogenesis inhibitor with anti-tumor activity. | ||
| M4695 | D-Pinitol | Anti-infection |
| D-pinitol (3-O-methyl-D-Chiro-inositol) is a natural compound found in several plants, such as pinaceae and legumes. D-pinitol has hypoglycemic activity and cardiovascular system protection. D-pinitol has antiviral and larvicidal activities. | ||
| M4732 | Palmitic acid | Metabolite/Endogenous Metabolite |
| Palmitic Acid (1.00509); Palmitic acid tech; Hexadecan acid | ||
| Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid (PA) can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells. Palmitic acid can be used to establish a cell steatosis model. | ||
| M4734 | Protopine | ROS |
| Corydinine | ||
| Protopine is a kind of isoquinoline alkaloid, which often exists in some plants in northeast Asia. It is mainly used to study the anti-tumor and anti-inflammatory activities. | ||
| M4740 | Corilagin | TNF Receptor |
| Corilagin is an inhibitor of TNF-α, discovered in many medicinal plants such as Phyllanthus speices etc., has multiple activities including anti-oxidative, anti-inflammatory, anti-apoptotic, hepatoprotective and others. | ||
| M4751 | 5,7-dihydroxychromone | PPAR |
| 5,7-dihydroxychromone is a natural antioxidant extracted from plants, it acts as an Nrf2/ARE signal activator or a PPARγ agonist. | ||
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