About 1 result found for searched term "AMG-8718 " (0.131 seconds)
Cat.No. | Name | Target |
---|---|---|
M27963 | AMG-8718 | Gamma-secretase/Beta-secretase |
AMG-8718 is a potent, selective and orally active BACE1 inhibitor with IC50 values of 0.0007, 0.005 µM for BACE1 and BACE2, respectively. AMG-8718 significantly decreases Aβ40 levels in the CSF and brain. |
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