About 1 result found for searched term "ADS032" (0.161 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M54576 | ADS032 | NLR |
| ADS032 is a dual inhibitor of NLRP1 and NLRP3 that rapidly, reversibly and stably inhibits inflammasome formation and reduces NLPR1 and NLRP3 activation of human-derived macrophages and bronchial epithelial cells to secrete and mature IL-1β and TNF-α, and reduces NLRP3-induced ASC speck formation. In addition, ADS032 protects mice from the deadly influenza A virus, reduces lung inflammation and improves survival. | ||
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