About 5 results found for searched term "ACV1" (0.125 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M24696 | Ascrinvacumab | ALK |
| Anti-ACVRL1/ALK-1 Reference Antibody; PF-03446962 | ||
| Ascrinvacumab (PF-03446962) is a human IgG2 monoclonal antibody targets ALK-1. Ascrinvacumab shows binding efficiency with human ALK1 with a Kd value of 7 nM. Ascrinvacumab can be used for the research of hepatocellular carcinoma (HCC). | ||
| M52755 | ACV1 | AChR/AChE |
| ACV1 (Vc1.1), an α-Conotoxin, is a selective α9α10 nAChR antagonist with an IC50 of 19 nM. | ||
| M13852 | Momelotinib sulfate | JAK |
| CYT387 sulfate salt | ||
| Momelotinib sulfate (CYT387 sulfate salt) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, 10-fold selectivity versus JAK3 (IC50=155 nM). In addition, Momelotinib is an inhibitor of activin A receptor type I (ACVR1). It may be used in studies related to myelofibrosis. | ||
| M49566 | Itacnosertib | JAK |
| Itacnosertib (TP-0184) is both inhibitor to JAK2, ACVR1 (ALK2) and ALK5 as described in WO2014151871. | ||
| M55353 | Recombinant Human BMP-9 Protein (E. coli, His Tag) | Cytokines and Growth Factors |
| Bone Morphogenetic Protein-9; GDF-2 | ||
| Bone Morphogenetic Protein-9 (BMP-9), also known as Growth differentiation factor 2 (GDF2), is an extracellular multifunctional cytokine that is also a member of the TGF-β family. BMP-9/GDF-2 selectively signals through ACVRL1 in endothelial cells. Additionally, it engages in high-affinity interactions with ENG, forming a heterotetramer or a heteromeric complex with ENG and ACVRL1. | ||
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