About 10 results found for searched term "AC 187" (0.134 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3971 | Isosteviol | ROS |
| Ketoisostevic Acid,NSC 231875 | ||
| Isosteviol is a tetracyclic diterpenoid obtained by acid hydrolysis of steviol glycoside extracts isolated from abundant Stevia rebaudiana plants. | ||
| M5611 | Embelin | IAP |
| Embelic acid; Emberine; NSC 91874 | ||
| Embelin is a cell-permeable benzoquinone compound that exhibits antitumor properties. Specifically antagonizes XIAP-mediated inhibition of caspase-9 activation by directly targeting the Smac and caspase-9 binding domain BIR3 (IC50 = 4.1 uM in a competitive binding assay with Smac peptide). | ||
| M50214 | AC 187 TFA | Amyloid |
| AC 187 TFA is a potent, orally active and neuroprotective amylin receptor antagonist with an IC50 of 0.48 nM and a Ki of 0.275 nM. AC 187 TFA is more selective for amylin receptors than calcitonin and CGRP receptors. | ||
| M53274 | AC 187 | Others |
| AC 187 is a potent and orally active amylin receptor antagonist with an IC50 of 0.48 nM and a Ki of 0.275 nM. | ||
| M5241 | GLPG0187 | Integrin |
| GLPG0187 inhibited the progression of bone metastasis. Maximum efficacy of inhibition of bone metastasis was achieved when GLPG0187 was combined with the standard-of-care metastatic breast cancer treatments. | ||
| M5254 | Ipragliflozin | SGLT |
| ASP 1941 | ||
| Ipragliflozin (ASP1941) is an orally active and selective SGLT2 inhibitor with IC50s of 7.38 and 1876 nM, 6.73 and 1166 nM, 5.64 and 1380 nM for human SGLT2 and SGLT1, rat SGLT2 and SGLT1, mouse SGLT2 and SGLT1, respectively. | ||
| M13441 | Recombinant Human IFN-β (HEK 293) | Cytokines and Growth Factors |
| Recombinant human IFN-β protein (HEK 293) acts through STAT1 and STAT2 and is known to up-regulate and down-regulate a number of genes, most of which are involved in antiviral immune responses. Protein structure: IFN-β (MET22-ASN187), Accession # P01574. | ||
| M30373 | SP187 | Anti-infection |
| MON-DNJ; UV4 | ||
| SP187 is a host-targeted iminosugar with activity against filovirus infections in vitro and in vivo. SP187 is active against influenza and dengue in vivo. | ||
| M49566 | Itacnosertib | JAK |
| Itacnosertib (TP-0184) is both inhibitor to JAK2, ACVR1 (ALK2) and ALK5 as described in WO2014151871. | ||
| M52759 | α-Conotoxin EI | AChR/AChE |
| α-Conotoxin EI is a selective nicotinic acetylcholine α1β1γδ receptor (nAChR) antagonist (IC50=187 nM) and an α3β4 receptor inhibitor. | ||
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