About 1 result found for searched term "A-9758 " (0.13 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29140 | A-9758 | ROR |
| A-9758 is a RORγ ligand and a potent, selective RORγt inverse agonist (IC50=5 nM), and exhibits robust potency against IL-17A release. A-9758 is effective in suppressing both Th17 differentiation and Th17 effector function. A-9758 significantly attenuates IL-23 driven psoriasiform dermatitis and is effective in blocking skin and joint inflammation. | ||
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