About 2 results found for searched term "996-19-0" (0.133 seconds)
Cat.No. | Name | Target |
---|---|---|
M7601 | Aminoguanidine hemisulfate salt | Others |
Inhibits both constitutive and inducible nitric oxide synthetase. | ||
M28491 | MRT199665 | Salt-inducible Kinase |
MRT199665 is a potent and ATP-competitive, selective MARK/SIK/AMPK inhibitor with IC50s of 2/2/3/2 nM, 10/10 nM, and 110/12/43 nM for MARK1/MARK2/MARK3/MARK14, AMPKα1/AMPKα2, and SIK1/SIK2/SIK3, respectively. MRT199665 causes apoptosis in MEF2C-activated human acute myeloid leukemias (AML) cells. MRT199665 inhibits the phosphorylation of SIK substrate CRTC3 at S370. |
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