About 1 result found for searched term "945619-74-9" (0.128 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4131 | Ophiopogonin D | PPAR |
| 65604-80-0; 945619-74-9 | ||
| Ophiopogonin D, isolated from the tuber of Ophiopogon japonicus, is a rare naturally occurring C29 steroid glycoside. Ophiopogonin D is a CYP2J3 inducer. By increasing the expression of CYP2J2/EETs and PPARα in human umbilical vein endothelial cells (HUVECs), Ophiopogonin D significantly inhibited Ang Ii-induced NF-κB nuclear translocation and IκBα down-regulation. Intracellular Ca2+ overload and activation of pro-inflammatory cytokines. | ||
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