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 About 1 result found for searched term "916232-21-8" (0.123 seconds)

Cat.No.  Name Target
M6766 GS143 IκB/IKK
GS-143
GS143 is a β-TrCP1 ligase inhibitor. GS143 is a selec­tive IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation. GS143 sup­presses NF-κB acti­va­tion and tran­scrip­tion of tar­get genes and does not inhibit proteasome activity.



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