About 1 result found for searched term "900308-51-2" (0.12 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M30840 | SEC inhibitor KL-2 | Others |
| KL-2 | ||
| SEC inhibitor KL-2 (KL-2), a peptidomimetic lead compound, is a potent, selective super elongation complex (SEC) inhibitor and disrupts the interaction between the SEC scaffolding protein AFF4 and P-TEFb, resulting in impaired release of Pol II from promoter-proximal pause sites and a reduced average rate of processive transcription elongation. SEC inhibitor KL-2 exhibits an dose-dependent inhibitory effect on AFF4-CCNT1 interaction with a Ki of 1.50 μM. | ||
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