About 1 result found for searched term "863406-85-3" (0.079 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M30727 | Zoniporide hydrochloride hydrate | Na+/H+ Exchanger (NHE) |
| CP-597396 hydrochloride hydrate | ||
| Zoniporide (CP-597396) hydrochloride hydrate is a potent and selective inhibitor of sodium-hydrogen exchanger type 1 (NHE-1). Zoniporide hydrochloride hydrate inhibits human NHE-1 (IC50=14 nM), and has >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride hydrate potently inhibits ex vivo NHE-1-dependent swelling of human platelets (IC50=59 nM). | ||
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