About 9 results found for searched term "86-34-0" (0.354 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2229 | Leflunomide | DHODH |
| HWA486; RS-34821; SU101 | ||
| Leflunomide (HWA486) is an inhibitor of dihydroorotate dehydrogenase with IC50 of 2.5 μM. | ||
| M6855 | JW 74 | Wnt/beta-catenin |
| JW 74 is a wnt pathway inhibitor, with an IC50 of 420 nM. JW 74 targets the β-catenin destruction complex (GSK-3 beta /AXIN/APC). JW 74 increases AXIN2 and decreases active β-catenin levels in colorectal cancer (CRC) cells. | ||
| M14752 | Phensuximide | Others |
| Phensuximide is an orally active succinimide antiepileptic and anticonvulsant agent. Phensuximide inhibits cyclic AMP and cyclic GMP accumulation in depolarized brain tissue. Phensuximide can be used for the study of seizure and petit mal. | ||
| M20141 | WAY-333875 | Others |
| WAY-333875 altering the lifespan of a eukaryotic organism | ||
| M30727 | Zoniporide hydrochloride hydrate | Na+/H+ Exchanger (NHE) |
| CP-597396 hydrochloride hydrate | ||
| Zoniporide (CP-597396) hydrochloride hydrate is a potent and selective inhibitor of sodium-hydrogen exchanger type 1 (NHE-1). Zoniporide hydrochloride hydrate inhibits human NHE-1 (IC50=14 nM), and has >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride hydrate potently inhibits ex vivo NHE-1-dependent swelling of human platelets (IC50=59 nM). | ||
| M43644 | Euphoheliosnoid A | Others |
| Euphoheliosnoid A is a diterpenoid that can significantly enhance the killing activity of natural killer (NK) cells towards H1299-luci cells and A549-luci cells at the concentration of 2.5 μM. | ||
| M49442 | BMS-986340 | CCR |
| BMS-986340 is a human immunoglobulin G1 (IgG1) non-fucosylated (NF) monoclonal antibody to CCR8 that targets, binds to, and blocks CCR8 activity on CCR8-positive tumor-infiltrating regulatory T-cells (Tregs) in tumor microenvironments (TMEs) and prevents chemokine ligand (CCL1-CCR8)-mediated signaling. | ||
| M49780 | SJ1008030 | PROTAC |
| SJ1008030 is a JAK2 PROTAC which selectively degrades JAK2. | ||
| M53567 | GE 2270A | Antibiotic |
| GE 2270A (MDL 62879) is an antibiotic. | ||
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