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 About 1 result found for searched term "850140-73-7" (0.123 seconds)

Cat.No.  Name Target
M5307 Afatinib dimaleate EGFR/HER2
BIBW 2992MA2; BIBW2992; Afatinib
Afatinib (BIBW2992) Dimaleate irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R), EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively; 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant.



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