About 9 results found for searched term "83-86-3" (0.06 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5313 | AZD2932 | VEGFR/PDGFR |
| AZD2932 is a potent and mutil-targeted protein tyrosine kinase inhibitor with IC50 of 8 nM, 4 nM, 7 nM, and 9 nM for VEGFR-2, PDGFRβ, Flt-3, and c-Kit, respectively. | ||
| M10380 | dBET57 | PROTAC |
| dBET-57 | ||
| dBET57 is a novel BRD4 heterobifunctional small-molecule ligand (PROTAC) which exhibits significant and selective degradation of BRD4 BD1 but is inactive on BRD4 BD2. | ||
| M21007 | Phytic acid | Others |
| inositol polyphosphate, inositol hexakisphosphate | ||
| Phytic acid is the principal storage form of phosphorus in many plant tissues, especially bran and seeds. It can act as a cofactor in DNA repair by nonhomologous end-joining. | ||
| M21786 | ACT-709478 | Calcium Channel |
| NBI-827104 | ||
| ACT-709478 is a selective, orally active and brain-penetrating T-type calcium channel blocker (Cav3.1, Cav 3.2, Cav 3.3). | ||
| M28628 | (-)-Irofulven | DNA Alkylator/Crosslinker |
| MGI 114; 6-Hydroxymethylacylfulvene; NSC 683863 | ||
| (-)-Irofulven (MGI 114), an Illudin S analog, is a DNA alkylating agent. (-)-Irofulven inhibits the replication of DNA, induces tumor cells apoptosis, and has potent antitumor activity. | ||
| M38825 | Isoharringtonine | Apoptosis |
| Isoharringtonine is a natural alkaloid that can be purified from Cephalotaxus koreana Nakai. Isoharringtonine can inhibit cancer cell proliferation and migration, and induce cancer cell apoptosis. Isoharringtonine can be used for the research of cancers. | ||
| M39141 | Nelumol A | Farnesoid X Receptor |
| Nelumol A is a farnesoid X receptor (FXR) agonist. | ||
| M43413 | ERD-3111 | Estrogen Receptor |
| ERD-3111 is an orally active PROTAC ERα degrader (DC50: 0.5 nM). | ||
| M50481 | TRH-AMC | Others |
| TRH-AMC is a fluorogenic substrate used in a coupled assay for thyrotropin-releasing hormone(TRH)-degrading ectoenzyme. | ||
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