83-72-7 - Search Results | AbMole BioScience

About 6 results found for searched term "83-72-7" (0.123 seconds)

Cat.No.	Name	Target
M5878	Pioglitazone HCl	PPAR
	AD-4833, U-72107E
	Pioglitazone HCl is a selective peroxisome proliferator-activated receptor-gamma (PPARgamma) agonist, used to treat diabetes.
M13380	Tapotoclax	Bcl-2
	AMG-176；CS-2836
	Tapotoclax is an inhibitor of myeloid leukemia cell differentiation protein McL-1 (myeloid leukemia-1) with a Ki value of 0.13 nM and has potential pro-apoptotic and anti-tumor activity.
M18211	2-Hydroxy-1,4-naphoquinone	Antifungal
	2-Hydroxy-1,4-naphoquinone
M53611	Crotalicidin	Antibiotic
	Crotalicidin is an antimicrobial peptide and anti-tumor peptide that can effectively inhibit the activity of Gram-negative bacteria and tumor cells.
M24888	Cetrelimab	PD-1/PD-L1
	JNJ 63723283; JNJ 3283
	Cetrelimab (JNJ 63723283; JNJ 3283) is a humanized IgG4κ mAb targeting PD-1. Cetrelimab binds PD-1 (Kd=1.72 nM, HEK293) to block the interaction of PD-1 with PD-L1 and PD-L2 (IC50s=111.7 ng/mL and 138.6 ng/mL, respectively). Cetrelimab stimulates peripheral T cells, increases IFN-γ, IL-2, TNF-α level and inhibits tumor growth in vivo.
M55296	VVD-214	DNA/RNA Synthesis
	RO7589831
	VVD-214 (RO7589831) is a synthetic lethal allosteric inhibitor of WRN helicase. VVD-214 covalently binds to cysteine 727 of WRN and inhibits ATP hydrolysis and helicase activity.