About 1 result found for searched term "79902-63-9" (0.12 seconds)
Cat.No. | Name | Target |
---|---|---|
M3497 | Simvastatin (MK 733) | Autophagy |
MK 733; MK-0733 | ||
Simvastatin (MK-0733, MK 733) is a competitive inhibitor of HMG-CoA reductase with Ki of 0.1-0.2 nM in cell-free assays. Simvastatin induces ferroptosis, mitophagy, autophagy and apoptosis. Simvastatin inhibits exosome release. Prior to use in cell assays, Simvastatin needs to be activated by NaOH in EtOH treatment. |
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