About 8 results found for searched term "75-12-7" (0.052 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3483 | Flavopiridol hydrochloride | CDK |
| NSC 649890 HCl; Alvocidib hydrochloride; L86 8275 HCl; HMR-1275 HCl | ||
| Flavopiridol competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM. It is 7.5-fold more selective for CDK1/2/4/6 than CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. | ||
| M13718 | Onvansertib | PLK |
| PCM-075; NMS-1286937; NMS-P937 | ||
| Onvansertib (PCM-075, NMS-1286937, NMS-P937) is a first-in-class, third-generation, oral, highly selective PLK1 inhibitor that induces tumor cell arrest in the G2/M phase and triggers apoptosis. It has a median IC50=136nM against a variety of CRC cell lines and inhibits xenograft models such as HT-29, HCT-116, and Colo-205 well. | ||
| M20950 | N-Acetylglucosamine | Metabolite/Endogenous Metabolite |
| GlcNAc | ||
| N-Acetylglucosamine is a monosaccharide that usually polymerizes linearly through (1,4)-β-linkages. It may be helpful for the treatment of autoimmune diseases. | ||
| M25539 | Formamide | Solvents & Excipients |
| Methanamide; Formimidic acid | ||
| Formamide is an amide derived from formic acid and has been used as solvent for many ionic compounds. | ||
| M43027 | Ethychlozate | Others |
| Ethychlozate is a plant growth regulator on the promotion of flowering in citrus. | ||
| M51237 | TREM-1 inhibitory peptide GF9 | Others |
| TREM-1 inhibitory peptide GF9 (Human TREM-1(213-221)) is a ligand‐independent TREM‐1 inhibitory nonapeptide GF9 that can blunt excessive inflammation caused by rheumatoid arthritis (RA). | ||
| M52483 | (Asp37)-Amyloid β-Protein (1-42) | Amyloid |
| (Asp37)-Amyloid β-Protein (1-42) is the G37D mutant of wild-type Amyloid-beta (1-42) peptide. | ||
| M53540 | P1 | Antibiotic |
| P1 is a broad-spectrum antimicrobial peptide. | ||
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