About 6 results found for searched term "75-04-7" (0.12 seconds)
Cat.No. | Name | Target |
---|---|---|
M1771 | Ataluren | CFTR |
PTC124 | ||
Ataluren (PTC124) is a novel, orally available small molecular CFTR-G542X nonsense allele inhibitor. | ||
M44014 | Ethylamine | Others |
Ethylamine | ||
M49548 | VVD-118313 | JAK |
VVD-118313 is a potent, selective JAK1 inhibitor. | ||
M58014 | YJG-1 | Others |
YJG-1 | ||
M28529 | ML375 | AChR/AChE |
VU0483253 | ||
ML375 (VU0483253) is a potent, highly selective, brain-penetrant and orally active M5 mAChR negative allosteric modulator (NAM) with IC50s of 300 nM and 790 nM for human and rat M5, respectively. ML375 is inactive at human and rat M1-M4. | ||
M55627 | RO-275 | HCN Channel |
RO-275 is a potent, selective and orally active HCN1 inhibitor with IC50 values of 0.046, 14.3, 4.6, 13.9 µM for HCN1, HCN2, HCN3, HCN4, respectively. The selective HCN1 inhibitor RO-275 improved performance in a translationally relevant touchscreen task of WM (TUNL) in rats. |
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