About 1 result found for searched term "706808-37-9" (0.136 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M55036 | Belatacept | Immunology/Inflammation |
| BMS 224818; LEA 29Y | ||
| Belatacept (BMS 224818) is a fusion protein composed of the Fc fragment of a human IgG1 immunoglobulin linked to the extracellular domain of CTLA-4, which is a molecule crucial in the regulation of T cell costimulation, selectively blocking the process of T-cell activation. Belatacept binds to CD 80/86 ligands and thereby inhibits the CD-28-mediated T-cell costimulation. Belatacept can be used in the research of Immunosuppression in organ transplants. | ||
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