About 13 results found for searched term "70-53-1" (0.121 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M40981 | PF-07055341 | DGAT |
| PF-07055341 is a DGAT1/2 inhibitor that can be used in studies related to non-alcoholic steatohepatitis (NASH). | ||
| M52341 | DL-Lysine Monohydrochloride | Amino Acid Derivatives |
| DL-Lysine Monohydrochloride is a lysine derivative. | ||
| M52775 | α-Conotoxin PnIA | AChR/AChE |
| α-Conotoxin PnIA, a potent and selective antagonist of the mammalian α7 nAChR, has the potential for the research of neurological conditions such as neuropathic pain and Alzheimer’s disease. | ||
| M7220 | RS 17053 hydrochloride | Others |
| RS 17053 hydrochloride is a α 1A antagonist. | ||
| M25593 | PF-07081532 | GLP Receptor |
| Lotiglipron | ||
| PF-07081532 is a next-generation orally active GLP-1 receptor agonist. | ||
| M20833 | Vodobatinib (K0706) | Src-bcr-Abl |
| SCO-088, SUN K706, SUN-K0706 | ||
| Vodobatinib (K0706, SCO-088, SUN K706, SUN-K0706) is a novel BCR-ABL1 tyrosine kinase inhibitor with an IC50 of 7 nM. Vodobatinib exhibits activity against most BCR-ABL1 point mutants with IC50s of 167 nM, 154 nM,165 nM and 1967 nM for BCR-ABL1L248R, BCR-ABL1Y253H , BCR-ABL1E255V and BCR-ABL1T315I, respectively. | ||
| M28775 | UNC-2170 | Others |
| UNC-2170 is a functionally active, fragment-like ligand for 53BP1 (IC50=29 µM; Kd=22 µM). UNC-2170 shows at least 17-fold selectivity for 53BP1 as compared to nine other methyl-lysine (Kme) reader proteins. 53BP1 is a Kme binding protein that plays a central role in DNA Damage Repair (DDR) pathways and is recruited to sites of double-strand breaks (DSB). | ||
| M29109 | AZ13705339 | PAK |
| AZ13705339 is a highly potent and selective PAK1 inhibitor with IC50s of 0.33 nM and 59 nM for PAK1 and pPAK1, respectively. AZ13705339 has binding affinities to PAK1 and PAK2, with Kds of 0.28 nM and 0.32 nM, respectively. AZ13705339 can be used in the research of cancers. | ||
| M29759 | SZ-015268 | CDK |
| SZ-015268 is a CDK7 inhibitor with an IC50 of 23.56 nM. SZ-015268 has extremely significant anti-tumor advantages. SZ-015268 inhibits HCC70, OVCAR-3, HCT116 and HCC1806 cells proliferation with IC50s of 33, 80.56, 12.53, and 61.55 nM, respectively. | ||
| M30058 | YM-1 | HSP |
| YM-1 is a stable and soluble MKT-077 analog and an orally active Hsp70 inhibitor. YM-1 induces cell death of HeLa cells and up-regulates the level of p53 and p21 proteins. | ||
| M31006 | AZ13705339 hemihydrate | PAK |
| AZ13705339 hemihydrate is a highly potent and selective PAK1 inhibitor with IC50s of 0.33 nM and 59 nM for PAK1 and pPAK1, respectively. AZ13705339 hemihydrate has binding affinities to PAK1 and PAK2, with Kds of 0.28 nM and 0.32 nM, respectively. AZ13705339 hemihydrate can be used in the research of cancers. | ||
| M56261 | BMS-470539 | Melanocortin Receptor |
| BMS-470539 is a synthetic MC-1R agonist with potent anti-inflammatory properties. | ||
| M56259 | BMS-470539 dihydrochloride | Melanocortin Receptor |
| BMS-470539 dihydrochloride is a highly potent and selective melanocortin-1 receptor (MC-1R) agonist with an IC50 of 120 nM, an EC50 of 28 nM. | ||
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