About 7 results found for searched term "67-97-0" (0.119 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5515 | Vitamin D3 | Vitamin |
| Cholecalciferol; Colecalciferol | ||
| Vitamin D3 (Cholecalciferol) is a form of vitamin D, binds and activates a H305F/H397Y mutant vitamin D receptor (VDR) with EC50 of 300 nM. *The compound is unstable in solutions, freshly prepared is recommended | ||
| M6542 | BVT 948 | Others |
| BVT 948 is a non-competitive protein tyrosine phosphatase inhibitor; enhances insulin signaling. | ||
| M53184 | N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA | FPR |
| N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA (For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA) is a formyl peptide receptor (FPR) agonist. | ||
| M13414 | PF-06751979 | BACE |
| PF-06751979 is a potent, brain permeable inhibitor of β -amyloid precursor protein lyase 1 (BACE1) with an IC50 of 7.3 nM. | ||
| M21195 | JNJ-67569762 | Others |
| JNJ-67569762 is a selective BACE1 inhibitor targeting S3 (IC50 = 2.7 nM). It is a preclinical candidate compound for the study of Alzheimer's disease. | ||
| M29932 | AZ10397767 | CXCR |
| AZ10397767 is an orally active, selective CXCR2 receptor antagonist with an IC50 of 1 nM. AZ10397767 attenuates the Oxaliplatin-induced NF-κB transcriptional activity and potentiates Oxaliplatin-induced apoptosis in androgen-independent prostate cancer (AIPC) cells. AZ10397767 significantly inhibits neutrophil recruitment into tumors which then adversely affects tumor growth in vitro and in vivo. | ||
| M41642 | Bromodomain IN-2 | Epigenetic Reader Domain |
| BD-IN-1 is a pan bromodomain (BD) inhibitor with KD values of 250, 420, 130, 430, 67, 240, 970 nM for BRD4(1), CBP, BRPF1B, BRD7, BRD9, BRDT(1), CECR2 respectively. | ||
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