About 6 results found for searched term "64-77-7" (0.122 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2332 | Zileuton | Lipoxygenase |
| A 64077; Abbott 64077 | ||
| Zileuton is an orally active 5-lipoxygenase (5-LOX) inhibitor that inhibits LTB4 synthesis with IC50 values of 0.56, 2.3 and 2.6 μM in dog, rat and human blood respectively. | ||
| M3077 | Tolbutamide | Potassium Channel |
| HLS 831 | ||
| Tolbutamide is an inhibitor of cAMP with IC50 of 4 mM, it is also an inhibitor of potassium channel, used for type II diabetes. | ||
| M17765 | Ginsenoside Rk3 | Triterpenoids |
| Ginsenoside Rk3 | ||
| M49909 | ML230 | BCRP/ABCG2/MXR/ABCP |
| CID44640177; SID 88095709 | ||
| ML230 is a selective inhibitor of the ATP-binding transporter subtype ABCG2, and its inhibitory effect on ABCG2 was 36 times that of ABCB1, with EC50 values of 0.13 μM and 4.65 μM, respectively. | ||
| M8095 | PF-06409577 | AMPK |
| PF-6409577 | ||
| Pf-06409577 is a potent and selective allosteric activator of AMPK α1β1γ1 subtype with an EC50 value of 7 nM. | ||
| M20771 | RP-64477 | Others |
| RP-64477 is a potent inhibitor of the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT). RP-64477 inhibits ACAT activity with IC50 of 113 nM, 503 nM, and 180 nM in human intestinal (CaCo-2), hepatic (HepG2) and monocytic (THP-1) cell assays, respectively. | ||
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