About 2 results found for searched term "637-21-8" (0.132 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M44879 | Homatropine hydrochloride | AChR/AChE |
| Homatropine hydrochloride is an orally active anticholinergic agent that rapidly dilates pupils and has cycloplegic effects. | ||
| M28688 | PF-06372865 | GABA Receptor |
| Darigabat | ||
| PF-06372865 is an orally active, α2/α3/α5 subtype-selective GABAA positive allosteric modulator (PAM). PF-06372865 is a high affinity ligand at GABAA receptors containing α1/α2/α3/α5 subunits (Kis of 2.9 nM, 21 nM, 134 nM for α2, α1 PAM, α2 PAM, respectively), with low affinity for α4/α6 subunits. PF-06372865 can across the blood-brain barrier (BBB). PF-06372865 has anxiolytic activity and has the potential for epilepsy. | ||
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