About 1 result found for searched term "62637-93-8" (0.126 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M54724 | Trimethylamine N-oxide dihydrate | Pyroptosis |
| Trimethylamine N-oxide dihydrate is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients.Trimethylamine N-oxide dihydrate induces inflammation by activating ROS/NLRP3 inflammasome, and also accelerates fibroblast differentiation and induces cardiac fibrosis by activating TGF-β/smad2 signaling pathway. In addition, Trimethylamine N-oxide dihydrate induces tumor cell pyroptosis and enhances CD8+ T cell-mediated antitumor responses in triple-negative breast cancer. | ||
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