About 7 results found for searched term "62-33-9" (0.056 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M16860 | Jasnervoside G | Iridoids |
| Jasnervoside G | ||
| M21014 | edetate calcium disodium | Others |
| EDTA calcium disodium | ||
| Edetate calcium disodium is a chelating agent that is primarily used for the management of severe lead poisoning. | ||
| M21478 | ELX-02 disulfate | p53 |
| NB-124 disulfate | ||
| ELX-02 disulfate (NB-124 disulfate) is a first-in-class synthetic eukaryotic ribosomal specific glycoside (ERSG) that can be used to study genetic diseases caused by nonsense mutations. | ||
| M28601 | NVS-SM2 | DNA/RNA Synthesis |
| NVS-SM2 is a potent, orally active and brain-penetrant SMN2 splicing enhancer with an EC50 of 2 nM for SMN. NVS-SM2 enhances U1-pre-mRNA association. NVS-SM2 promotes exon 7 inclusion and restores normal survival motor neuron (SMN) protein expression. NVS-SM2 can be used for spinal muscular atrophy (SMA) research. | ||
| M28706 | SF0166 | Integrin |
| SF0166 is a potent and selective αvβ3 antagonist with IC50 values of 0.6 nM, 8 nM, and 13 nM for αvβ3, αvβ6, and αvβ8, respectively. SF0166 inhibits cellular adhesion to vitronectin across human, rat, rabbit, and dog cell lines with IC50 values of 7.6 pM to 76 nM. SF0166 decreases neovascularization in the oxygen-induced retinopathy mouse model. | ||
| M38925 | Ivaltinostat | HDAC |
| Ivaltinostat (CG-200745) is an orally active, potent pan-HDAC inhibitor which inhibits deacetylation of histone H3 and tubulin. Ivaltinostat induces the accumulation of p53, promotes p53-dependent transactivation, and enhances the expression of MDM2 and p21 (Waf1/Cip1) proteins. | ||
| M50222 | Branaplam hydrochloride | DNA/RNA Synthesis |
| LMI070 hydrochloride; NVS-SM1 hydrochloride | ||
| Branaplam hydrochloride is an orally active, brain-permeable, selective modulator of SMN2 splicing, with an EC50 of 20 nM for SMN, and enhances full-length SMN protein and prolongs survival in a mouse model of severe spinal muscular atrophy (SMA). Branaplam hydrochloride also inhibits hERG with an IC50 of 6.3 μM. | ||
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