6-Prenylnaringenin - Search Results

About 5 results found for searched term "6-Prenylnaringenin" (0.13 seconds)

Cat.No.	Name	Target
M5172	6-Prenylnaringenin	GABA Receptor
	(2S)-6-Prenylnaringenin
	(2S)-6-Prenylnaringenin acts as a GABAA positive allosteric modulator at α+β- binding interface.
M16606	6-Methyl-8-prenylnaringenin	Flavonoids
	6-Methyl-8-prenylnaringenin
M30477	6,8-Diprenylnaringenin	BCRP/ABCG2/MXR/ABCP
	Lonchocarpol A; Senegalensin
	6,8-Diprenylnaringenin (Lonchocarpol A; Senegalensin), a hop prenylflavonoid, is a inhibitor of breast cancer resistance protein (BCRP/ABCG2). 6,8-Diprenylnaringenin inhibits ABCG2-mediated efflux of Mitoxantrone, and 3H-Methotrexate transport (IC50=0.41 μM) in HEK293 cells. 6,8-Diprenylnaringenin exhibits some estrogenicity, but its potency is less than 1% of that of 8-Prenylnaringenin.
M30485	(2R/S)-6-PNG	Calcium Channel
	6-Prenylnaringenin; (±)-6-Prenylnaringenin
	(2R/S)-6-PNG (6-Prenylnaringenin) is a potent and reversible Cav3.2 T-type Ca2+ channels (T-channels) blocker. (2R/S)-6-PNG can penetrate the blood-brain barrier (BBB). (2R/S)-6-PNG suppresses neuropathic and visceral pain in mice.
M30486	(±)-8-Prenylnaringenin	Estrogen Receptor
	(±)-8-Prenylnaringenin, a natural prenylated flavonoid, is a potent phytoestrogen. (±)-8-Prenylnaringenin is an orally active selective estrogen receptor modulator (SERM) (Estrogen Receptor/ERR) that inhibits ERα and ERβ with IC50s of 57 nM and 68 nM, respectively. (±)-8-Prenylnaringenin has anticancer effects, and can be used for osteoporosis research.