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 About 4 results found for searched term "58-39-9" (0.347 seconds)

Cat.No.  Name Target
M5083 β-Cyclodextrin Anti-infection
β-Cyclodextrin affects the formation of isomerization products during peptide deamidation.
M5872 Perphenazine Dopamine Receptor
Perphenazine, Perphenazin, Trilafon, Etaperazine
Perphenazine is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.
M2945 Pimozide Dopamine Receptor
R6238
Pimozide is an antagonist of 6-hydroxyapatide against 6-hydroxyapatide, with Ki values of 1.4 nM, 2.5 nM and 588 nM for 6-hydroxyapatide, D3 and D1 receptors, respectively. Pimozide also has a high affinity for α1-adrenoceptor. Ki value is 39 nM. Pimozide is also an inhibitor of STAT3 and STAT5, and piperimidate triggers ADCD in glioblastoma cell lines (LN-229, MZ-54, GOS-3 and U343) by inducing dephosphorylation and inactivation of mTORC1.
M11287 JNJ-39758979 Histamine Receptor
Jnj-39758979 is a selective, orally active, high-affinity histamine H4 receptor antagonist with Ki values of 12.5, 5.3 and 25 nM for human, mouse and monkey histamine H4 receptor, respectively. Jnj-39758979 antagonized histamine-induced cAMP inhibition with a pA2 of 7.9. Jnj-39758979 has good anti-inflammatory and antipruritic effects.



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