About 2 results found for searched term "57-66-9" (0.084 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1703 | Deforolimus | mTOR |
| Ridaforolimus, AP23573, MK-8669 | ||
| Deforolimus (also known as AP23573 and MK-8669) is an investigational targeted and small-molecule mTOR inhibitor. *The compound is unstable in solutions, freshly prepared is recommended | ||
| M2960 | Probenecid | TRP Channel |
| Benemid | ||
| Probenecid is a classical competitive inhibitor of organic anion transport, which is also a TRPV2 agonist and an inhibitor of TAS2R16. Probenecid effectively inhibits the MRP1- and MRP2-mediated uptake of the ATP-dependent active vesicle N-ethylmaleimide-glutathione (NEM-GS). Probenecid can competitively or non-competitively inhibit the transport function of MRP2 for organic anions. In vitro studies have shown that probenecid significantly inhibits MRP2-dependent ATPase activity and blocks the efflux of substrates (such as glutathione conjugates, certain antibiotics and chemotherapeutic agents) by MRP2. In addition to MRP2, probenecid is also an effective inhibitor of MRP1. | ||
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