About 1 result found for searched term "548472-68-0" (0.19 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2185 | Nutlin-3 | Mdm2 |
| Nutlin-3 is a selective MDM2 (mouse double minute 2) antagonist with IC50 of 90 nM. Nutlin-3 induces apoptosis in cancer cells. Nutlin-3 treatment induces the expression of MDM2 and p21, and displays potent antiproliferative activity with IC50 of ~1.5 μM in cells with wild-type p53 such as HCT116, RKO and SJSA-1. | ||
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