About 7 results found for searched term "54-84-2" (0.057 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2002 | Canagliflozin | SGLT |
| JNJ 24831754ZAE; JNJ 28431754; JNJ 28431754AAA; TA 7284 | ||
| Canagliflozin is a potent, selective sodium glucose co-transporter 2 inhibitor. | ||
| M2185 | Nutlin-3 | Mdm2 |
| Nutlin-3 is a selective MDM2 (mouse double minute 2) antagonist with IC50 of 90 nM. | ||
| M3013 | SKLB1002 | VEGFR/PDGFR |
| SKLB1002 is a potent and ATP-competitive VEGFR2 inhibitor with IC50 of 32 nM. | ||
| M10955 | Daridorexant | OX Receptor |
| Daridorexant is an effective orexin receptor antagonist. It also has IC50s of 2 nM and 3 nM for the Ox1 receptor and Ox2 receptor, respectively. | ||
| M28985 | AMG PERK 44 | PERK |
| AMG PERK 44 is an orally active and highly selective PERK inhibitor with an IC50 of 6 nM. AMG PERK 44 has 1000-fold and 160-fold selectivity over GCN2 (IC50=7300 nM) and B-Raf (IC50 >1000 nM), respectively. AMG PERK 44 induces autophagy. | ||
| M30283 | Cinanserin hydrochloride | 5-HT Receptor |
| SQ 10643 | ||
| Cinanserin hydrochloride (SQ 10643) is a potent, selective and highly affinity 5-HT2 receptor antagonist with a Ki of 41 nM. Cinanserin hydrochloride has a much higher binding affinity for the 5-HT2 than for the 5-HT1 receptor (Ki of 3500 nM). Cinanserin is also an inhibitor of 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro. | ||
| M44050 | Cyclo(Tyr-Pro) | Others |
| Cyclo(Tyr-Pro) | ||
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