54-21-7 - Search Results | AbMole BioScience

About 5 results found for searched term "54-21-7" (0.056 seconds)

Cat.No.	Name	Target
M3024	Sodium salicylate	COX
	Salicylic acid sodium salt; 2-Hydroxybenzoic acid sodium salt
	Sodium salicylate is used in medicine as an analgesic and antipyretic.
M20689	Sparsentan (RE-021)	Endothelin Receptor
	PS-433540; RE-021; DARA-a; BMS-346567
	Sparsentan (PS-433540, RE-021, DARA) is a first-in-class, orally active, high-affinity dual antagonist of the endothelin type A receptor (ETA) and Angiotensin II type 1 (AT1) receptor, with Ki values of 9.3 and 0.8 nM, respectively.
M28584	STAD 2	PKA
	STAD 2 is a potent and selective disruptor of PKA-RII, with a Kd of 6.2 nM. STAD 2 disrupts interactions between PKA and AKAP in an isoform-selective manner. STAD 2 displays antimalarial activity through a PKA-independent mechanism.
M28586	LML134	Histamine Receptor
	LML134 (compound 18b) is an orally active and high selective Histamine 3 receptor (H3R) inverse agonist with Kis of 0.3 nM and 12 nM for hH3R cAMP and hH3R bdg. LML134 penetrates the brain rapidly, leading to high H3R occupancy, and disengages its target with a fast kinetic profile. LML134 has the potential for excessive sleep disorders.
M55785	ML267	Antibiotic
	ML267 a potent Sfp phosphopantetheinyl transferase (PPTases) inhibitor with an IC50 of 0.29 μM.