About 4 results found for searched term "518-17-2" (0.174 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4436 | Evodiamine | Others |
| (+)-Evodiamine; d-Evodiamine | ||
| Evodiamine is an alkaloid isolated from the fruit of hemerocallis. It has a variety of biological activities, such as anti-inflammatory, anti-obesity and anti-tumor. | ||
| M1828 | Tandutinib | FLT3 |
| MLN518, CT53518 | ||
| Tandutinib (MLN518, CT53518) is an orally active multitargeted tyrosine kinase inhibitor of FLT3 (IC50 = 0.22 μM), and it also inhibits c-Kit and PDGFR with IC50 values of 0.17 μM and 0.20 μM, respectively. Tandutinib has the ability to cross the blood-brain barrier. | ||
| M2912 | Pacritinib | JAK |
| SB1518 | ||
| Pacritinib (SB1518) is an effective mutant inhibitor of wild-type JAK2 and JAK2V617F with IC50 of 23 nM and 19 nM, respectively. Pacritinib also inhibited FLT3 and its mutant FLT3D835Y with IC50 of 22 nM and 6 nM, respectively. | ||
| M14901 | Tandutinib hydrochloride | FLT3 |
| MLN518 hydrochloride; CT53518 hydrochloride | ||
| Tandutinib hydrochloride (MLN518 hydrochloride) is a potent and selective inhibitor of the FLT3 with an IC50 of 0.22 μM, and also inhibits c-Kit and PDGFR with IC50s of 0.17 μM and 0.20 μM, respectively. | ||
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
