About 10 results found for searched term "50-91-9" (0.053 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1782 | NSC 74859 (S3I-201) | STAT |
| S3I-201 | ||
| NSC 74859 (S3I-201) is a selective Stat3 inhibitor with an IC50 of 86 μM. NSC 74859 (S3I-201) is effective in hepatocellular cancers with disrupted TGF-beta signaling.*The compound is unstable in solutions, freshly prepared is recommended | ||
| M5648 | Floxuridine | DNA/RNA Synthesis |
| Deoxyfluorouridine; FUDR; NSC 27640 | ||
| Floxuridine (5-fluorouracil 2'-deoxyriboside) is a pyrimidine analogue that is also an antitumor metabolite of oncology. Floxuridine inhibits the Poly(ADP-Ribose) polymerase and induces DNA damage in vitro by activating ATM and ATR checkpoint signaling pathways. Floxuridine is an effective inhibitor of Staphylococcus aureus infection and can induce apoptosis. Floxuridine is resistant to HSV and CMV viruses. | ||
| M8796 | TCPOBOP | Others |
| TCPOBOP enhances the nuclear receptor CAR transactivation of cytochrome P450 (CYP), as dose-dependent direct agonist of CAR. | ||
| M10862 | MS645 | Epigenetic Reader Domain |
| MS645 is a BET bromodomains (BrD) inhibitor for K of BRD4-BD1/BD2i The value is 18.4 nM. MS645 spatially limits the divalent inhibition of BRD4 BrDs, resulting in sustained inhibition of BRD4 transcriptional activity in solid tumor cells. | ||
| M28723 | MW-150 | p38 MAPK |
| MW01-18-150SRM | ||
| MW150 (MW01-18-150SRM) is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM. MW-150 inhibits the ability of the endogenous p38α MAPK to phosphorylate an endogenous substrate MK2 in activated glia. | ||
| M29437 | CRT0066854 hydrochloride | PKC |
| CRT0066854 hydrochloride is a potent and selective atypical PKCs inhibitor. CRT0066854 is against full-length (FL) PKCι, PKCζ, and ROCK-II kinases with IC50 values of 132 nM, 639 nM, and 620 nM, respectively. | ||
| M39551 | 2-Amino-3,5-dibromobenzaldehyde | Others |
| 2-Amino-3,5-dibromobenzaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||
| M42010 | D-NAME hydrochloride | NO Synthase |
| D-NAME (D-NG-nitroarginine methyl ester) hydrochloride is a potent nitric oxide synthase (NOS) inhibitor. | ||
| M43345 | 10Panx | Others |
| 10Panx is a biological active peptide. | ||
| M54587 | IPG7236 | CCR |
| IPG7236 is a selective CCR8 antagonist that also exhibits significant tumor suppression in a mouse xenograft model of human breast cancer.IPG7236 can be used in cancer-related studies. | ||
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