About 5 results found for searched term "50-78-2" (0.053 seconds)
Cat.No. | Name | Target |
---|---|---|
M5426 | Aspirin | Animal Modeling |
Acetylsalicylic acid | ||
Aspirin is a salicylate, and irreversible COX1 and COX2 inhibitor, used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication. | ||
M13919 | Calhex 231 hydrochloride | Calcium-sensing Receptor |
Calhex 231 hydrochloride is a CaSR inhibitor via negative allosteric modulation. | ||
M18140 | Hydroxocobalamin hydrochloride | Metabolite/Endogenous Metabolite |
Hydroxocobalamin hydrochloride | ||
M24888 | Cetrelimab | PD-1/PD-L1 |
JNJ 63723283; JNJ 3283 | ||
Cetrelimab (JNJ 63723283; JNJ 3283) is a humanized IgG4κ mAb targeting PD-1. Cetrelimab binds PD-1 (Kd=1.72 nM, HEK293) to block the interaction of PD-1 with PD-L1 and PD-L2 (IC50s=111.7 ng/mL and 138.6 ng/mL, respectively). Cetrelimab stimulates peripheral T cells, increases IFN-γ, IL-2, TNF-α level and inhibits tumor growth in vivo. | ||
M49659 | MNK8 | STAT |
MNK8 is a potent STAT3 (signal transducer and activator of transcription 3) inhibitor. |
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