About 8 results found for searched term "50-55-5" (0.056 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2933 | PHA-408 | IκB/IKK |
| PHA-408 is a highly selective and ATP-competitive IKK-2 inhibitor with IC50 of 40 nM. | ||
| M4663 | Reserpine | Animal Modeling |
| Reserpine is an inhibitor of vesicular monoamine transporter protein 2 (VMAT2) that irreversibly blocks the H+-coupled vesicular monoamine transporters, VMAT1 and VMAT2. It can be used to construct animal models of depression. | ||
| M8531 | Liproxstatin-1 | Ferroptosis |
| Lip-1 | ||
| Liproxstatin-1 is a potent inhibitor of ferroptosis, a non-apoptotic form of cell death characterized by iron-dependent accumulation of lethal lipid reactive oxygen species (ROS). | ||
| M10936 | Taletrectinib | Trk |
| DS-6051b; AB-106; IBI-344 | ||
| Taletrectinib (DS-6051b) is a potent orally active next-generation selective ROS1/NTRK inhibitor. Taletrectinib is 0.207, 0.622, 2.28, and 0.98 nM, respectively IC50 It has a strong inhibitory effect on recombinant ROS1, NTRK1, NTRK2 and NTRK3. Taletrectinib also inhibits ROS1 G2032R and other ANTI-Crizotinib ROS1 mutants. | ||
| M13526 | A-1155463 | Bcl-2 |
| A1155463 | ||
| A-1155463 is a highly potent and selective BCL-XL inhibitor with an EC50 of 70 nM in Molt-4 cell. | ||
| M14453 | Enasidenib mesylate | Isocitrate Dehydrogenase (IDH) |
| AG-221 mesylate | ||
| Enasidenib mesylate is a first-in-class, oral, potent, reversible, selective inhibitor of the IDH2 mutant enzymes. | ||
| M41175 | HCV-IN-44 | Anti-infection |
| HCV-IN-44 is an HCV NS5B protein inhibitor that can effectively inhibit the replication of HCV virus. | ||
| M58027 | CS-1112 | Others |
| CS-1112 | ||
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