About 8 results found for searched term "5-Fluorouracil" (0.12 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2289 | 5-Fluorouracil | DNA/RNA Synthesis |
| 5-FU, Carac, Efudex; Adrucil | ||
| 5-Fluorouracil (5-FU) is a potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. | ||
| M39541 | 5-Chlorouracil (fluorouracil impurity) | Others |
| 5-Chlorouracil (Fluorouracil Impurity) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||
| M2247 | Carmofur | DNA/RNA Synthesis |
| HCFU | ||
| Carmofur is a pyrimidine analog that is a prodrug of 5-fluorouracil (5-FU), which inhibits DNA Synthesis and has better antiproliferative activity than 5-FU. Carmofur is an inhibitor of Acidic Ceramidase (ASAH1) and a potential lead compound for non-cancer diseases such as Krabbe disease, acute lung injury (ALI), Parkinson's disease (PD), dementia, etc. Carmofur also has antifungal and antimicrobial properties. | ||
| M5648 | Floxuridine | DNA/RNA Synthesis |
| Deoxyfluorouridine; FUDR; NSC 27640 | ||
| Floxuridine (5-fluorouracil 2'-deoxyriboside) is a pyrimidine analogue that is also an antitumor metabolite of oncology. Floxuridine inhibits the Poly(ADP-Ribose) polymerase and induces DNA damage in vitro by activating ATM and ATR checkpoint signaling pathways. Floxuridine is an effective inhibitor of Staphylococcus aureus infection and can induce apoptosis. Floxuridine is resistant to HSV and CMV viruses. | ||
| M8269 | 4-DAMP | AChR/AChE |
| 4-DAMP methiodide | ||
| 4-DAMP (4-DAMP methiodide) is a potent and selective antagonist of M3 receptors and also has a high affinity for the closely-related M5 receptors. 4-DAMP combined with 5-Fluorouracil (5-Fu) could significantly reduce the cell viability and enhance apoptosis in MKN45 and BGC823 gastric cancer cells. | ||
| M16195 | Thymine | Alkaloids |
| Thymine is one of the four bases of DNA that can be used as a target for 5-fluorouracil (5-FU) in animal cancer models with a Km value of 2.3 μM. | ||
| M19166 | Martynoside | Others |
| Martynoside protects ex vivo bone marrow cells from 5-fluorouracil (5-FU)-induced cell death and inflammation response by down-regulating the TNF signaling pathway. Martynoside is a potent antiestrogen in MCF-7 cells, increasing IGFBP3 levels | ||
| M21143 | 5-Fluorouridine | DNA/RNA Synthesis |
| 5-Fluorouridine is a metabolite of 5-fluorouracil, a potent inhibitor of nuclease autocleavage. 5-Fluorouridine binds to total and poly A RNA and has antiproliferative activity. 5-Fluorouridine induces apoptosis (cell death). | ||
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
