About 1 result found for searched term "5-(N,N-Hexamethylene)-amiloride" (0.117 seconds)
Cat.No. | Name | Target |
---|---|---|
M58160 | 5-(N,N-Hexamethylene)-amiloride | Sodium Channel |
Hexamethylene amiloride; HMA | ||
5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) is a potent Na+/H+ exchanger inhibitor, which decreases the intracellular pH (pHi) and induces apoptosis in leukemic cells. 5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) is also an inhibitor of the HIV-1 Vpu virus ion channel and inhibits mouse hepatitis virus (MHV) replication and human coronavirus 229E (HCoV229E) replication in cultured L929 cells with EC50s of 3.91 μM and 1.34 μM, respectively. |
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