About 3 results found for searched term "480-00-2" (0.233 seconds)
Cat.No. | Name | Target |
---|---|---|
M8037 | Sutezolid | Antibiotic |
PNU-100480; U-100480; PF-02341272 | ||
Sutezolid (PNU-100480), an orally active oxazolidinone antimicrobial agent, acts by inhibiting bacterial protein synthesis. Sutezolid has potent activity against mycobacteria, and is used for the research of drug-resistant tuberculosis. | ||
M38742 | Eleutherol | Antifungal |
Eleutherol is against yeasts Candida albicans, C. tropicalis, Saccharomyces cerevisiae and Cryptococcus neoformans with MIC values between 7.8 µg/mL and 250 µg/mL. Eleutherol inhibits α-glucosidase function with an IC50>1.00 mM. | ||
M20388 | AC480 (BMS-599626) | EGFR/HER2 |
AC480 (BMS-599626) is a selective and efficacious inhibitor of HER1 and HER2 with IC50 of 20 nM and 30 nM, ~8-fold less potent to HER4, >100-fold to VEGFR2, c-Kit, Lck, MET etc. Phase 1. |
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