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 About 1 result found for searched term "457081-03-7" (0.125 seconds)

Cat.No.  Name Target
M3737 Pyridone 6 JAK
Merck-5, CMP 6, JAK Inhibitor I
Pyridone 6 is a potent, reversible, cell-permeable, and ATP-competitive inhibitor of JAK1 (IC50 = 15 nM for murine JAK1), JAK2 (IC50 = 1 nM), JAK3 (Ki = 5 nM), and Tyk 2 (IC50 = 1 nM) (Janus protein tyrosine kinases).



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